Micro Electron Diffraction

Size does matter after all! We are talking about the size of your crystals, of course. Are they too tiny? Our motto is “no small crystal left behind!” We have the right tool for you: the electron diffractometer. This is the winning combination of your standard TEM and our fast hybrid-pixel electron detectors.

Taking advantage of the rotating stage of the transmission electron microscope, your sub-micron crystals can in fact provide you with high-resolution structural information using the continuous rotation electron diffraction method, introduced by Ute Kolb and colleagues more than a decade ago [ref 1]. While the methodology is not new, our fast SINGLA 1M detector will provide unprecedented data quality and super-fast readout for high-throughput shutterless data collection. We streamlined the small-molecule electron crystallography workflow to bring you outstanding results in less than four hours! [ref 2]

Our EIGER2-based electron detectors come in a number of formats that can be mounted on-axis onto a range of TEM configurations thanks to its vacuum flange adapter. We offer a choice of detector sizes ranging from a Quad up to a 1M.

You will increase your productivity with the staggering 2 kHz readout speed and achieve an unmatched dynamic range for your electron diffraction experiments, without compromise. No beam stop is necessary, and if you’re worried about damaging the detector with an intense 300 kV beam, we can deliver our detector with a thick Cadmium Telluride (CdTe) sensor. All our detectors are radiation-hard and worry-free by design.

What are you waiting for? Ask our experts about hybrid-pixel electron detectors to find the best solution for small-molecule electron crystallography.


Related news articles

Electron Diffraction of Submicron-Sized 3D Crystals


1. U. Kolb, T.E. Gorelik, et al. (2007) Ultramicroscopy 7, 507–513.
2. Tim Gruene et al. (2018) Angew. Chemie Int. Ed. 57, 16313-16317.


  • Direct electron detection
  • Region of interest feature
  • Up to 18'000 frames/sec
  • No dead time
  • Noise-free electron counting
  • 107 counts/pix/sec
  • No beam stop required
  • Ideal DQE also at low energies

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  • Electron-counting up to 107 electrons/pix/sec
  • Continuous readout at over 2,000 frames/sec
  • Can be integrated into the SerialEM package
  • Point-spread function ~1 at 100 kV