Pre-Clinical and Medical Research

Pre-clinicians and medical researchers have anticipated the arrival of detection techniques based on hybrid photon counting (HPC). This revolutionary technology detects every single X-ray photon to deliver the highest sensitivity, best possible image quality, and lowest patient dose.

Additionally, the spectral capabilities of the HPC detector offers pre-clinical medical research new ways of exploring and imaging established modalities, plus create new ones.

Targeting the Best Possible Image Quality

Combining a direct-detection sensor with a pixel size of 75 μm, DECTRIS detectors distinguish the finest details and achieve ultra-high resolution. That is essential for applications such as micro-CT, mammography, or digital breast tomosynthesis (DBT), where the smallest relevant micro-calcifications occur in the 100 μm range. The system’s modulation transfer function (MTF) shows nearly ideal behavior — far beyond that of currently available mammography detectors.

In-vivo spectral (color) CT of a living mouse administered with two nanoparticle contrast agents, liposomal iodine shown in the blood vessels (red) and liposomal gadolinium (green) accumulated in the tumor. Acquired with a DECTRIS spectral detector prototype enabling 4-material decomposition. (Courtesy of C. Badea, Duke University).

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