The PILATUS3 CMOS readout chips as well as the silicon sensors are designed using radiation-tolerant layout techniques developed for high-energy physics to prevent damage from incoming X-rays. The detectors are able to withstand the doses arising from long-term operation at modern synchrotrons.
[P. Kraft et al., J. Synchrotron Rad. (2009). 16, 368–375; doi:10.1107/S0909049509009911)]