DECTRIS SINGLA® detector is a fast, hybrid-pixel electron detector for a wide range of Life Sciences applications.

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DECTRIS SINGLA® detector is a hybrid-pixel electron-counting camera optimized for Life Sciences applications. With a sensitive area of roughly 1,000 x 1,000-pixels, it is suitable for Cryo-Electron Microscopy (cryoEM) and Micro-Electron Diffraction (microED) applications. Experiments in single-particle analysis and cryo-electron tomography also benefit greatly from this detector’s speed. In addition, SINGLA detector’s fast readout speed (exceeding 2,000 frames per second), combined with its superior dynamic range, make it the ideal detector for small-molecule and 3D micro-crystallography. The detector is bottom-mounted and compatible with JEOL and Thermo Fisher Scientific Transmission Electron Microscopes (TEM).

  • Fast & Accurate: detector’s direct electron detection at fast frame rate allow for optimal data collection at lower energies (100 keV), enabling low-dose electron microscopy.
  • Compatible: DECTRIS SINGLA® detector is compatible with the SerialEM program.

Detector Specifications*

Number of pixels (W x H)

1,028 x 1,062

Active area (W x H)




77.1 x 79.7 

Pixel size (W x H)




75 x 75

Sensor material

Silicon (Si)

Energy range




5.0 - 200

Frame rate (max.)




2,250 (16-bit); 4,500 (8-bit)

Count rate (max.)





Detective Quantum Efficiency, DQE(0)

0.9 at 100 kV, 0.8 at 200 kV

Detector mounting

Bottom, on-axis

*All specifications are subject to change without notice.
All technical documentation is available here.

SINGLA Technical Documentation

Key Contact

Luca Piazza
Product Manager - Electron Microscopy

Case Study

A purpose-built electron cryo-microscope with DECTRIS SINGLA, running at 100 keV, promises to reduce the cost and complexity of studies on biological structures.

Publication: McMullan, Greg, et al. "Structure determination by cryoEM at 100 keV." Proceedings of the National Academy of Sciences 120.49 (2023): e2312905120. 



Request a quote

If you are interested in trying out a DECTRIS SINGLA® hybrid-pixel electron detector in your experimental setup, contact us. 

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