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High resolution in situ PXRD studies in a lab? In two shots, please! When it comes to the tailored design of organic materials, inducing a physical or a chemical change with non-ambient conditions is a hot topic. Not only does this provide new paths for exploring the energy landscape, but it also allows chemistry to be green. In situ monitoring of temperature, pressure or mechanically induced phase transformations is the ultimate dream, as it provides exact information about the conditions at which a certain phase occurs [1,2].